Welcome to the Canadian chapter of the IWMF

If you have been diagnosed with Waldenstrom’s Macroglobulinemia, or care about someone who has, welcome to the IWMF family of WM patients, caregivers, friends and relatives. The page you are on is the home page for WMF Canada, which serves as the Canadian chapter of the International Waldenstrom’s Macroglobulinemia Foundation (IWMF).

Information for the newly diagnosed

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What’s New 

Article – Detection of MYD88 L265P

Article – WM Brochure

**2014 WMFC Educational Forum

Article – “MYD88 and CXCR4 Mutations in WM”

Click here for all news.  

Jan Gosta Waldenström (1906 – 1996)

 In 1944 the Swedish physician Jan Gosta Waldenström (1906 – 1996) identified a rare condition in which patients experienced a thickening of the serum (the liquid portion) of the blood. He described two patients who had bleeding in the area of the mouth and nose as well as in the retina of the eye, low red cell and platelet counts, high sedimentation rate, and lymph node involvement. Bone marrow biopsy showed excess lymphoid cells, yet there was no bone pain, excluding a diagnosis of multiple myeloma. Both patients had a large amount of a single unknown globulin with an extremely high molecular weight. We now know this globulin as IgM. His patients, as Dr. Waldenström himself described in 1961, had a “monoclonal gammopathy.”…learn more