As WM is an orphan disease, most current therapies are hand-me-downs from other cancers such as leukaemia, non-Hodgkin lymphoma and multiple myeloma. Clinical trials to evaluate new therapies for WM are rare, and fewer than 5% of cancer patients are willing or able to participate in a clinical trial. If we are to accelerate progress towards a cure, more of us need to step forward and participate in clinical trials.
There are three phases of clinical trials:
Phase 1 – establishes safe dosage of a new drug
Phase 2 – determines efficacy of new drug
Phase 3 – compares new drug against current therapies
For a comprehensive overview of the clinical trial process, and how to decide if a trial is for you, please view Dr. Gwen Nichol’s excellent presentation from the recent IWMF Educational Forum in Tampa.
You can click on the Clinical Trial number to be taken to the full trial description at clinical trials.gov.