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So far Daniel Zlatin has created 140 blog entries.

April 2020: Ibrutinib and Covid-19

2021-01-18T17:07:58-05:00

As a follow up to the article that appeared in Forbes magazine, Blood, the world’s leading haematology magazine, has published an article by Dr. Steve Treon. In the article, Dr. Treon explains the logic and process of ibrutinib’s possible effect on COVID-19. We have provided a .pdf of the article here. Of extra interest to WMFC members is the reference to the transgenic mouse model which has been through two stages of research that the WMFC has funded and supported with Dr. Treon at the Dana Farber Cancer Institute over the last five or six years. .PDF of Dr. Treon's [...]

April 2020: Ibrutinib and Covid-192021-01-18T17:07:58-05:00

Dec. 2020: Dr. Castillo Discusses Covid-19 Vaccines

2021-01-27T17:34:01-05:00

On Dec. 2, 2020, the Support Group leaders from across the US and Canada got together over Zoom.  There are three sections to the video.  The most important is the following one, given the current Covid situation: From approximately the 22 minute mark to the 34 minute point, Dr. Castillo of the Dana-Farber Bing Center discusses the leading Covid-19 candidates, and his take on their safety and efficacy in WM patients. The other two sections of the video include: From approximately 36:50 to 42:00, there is a discussion of topics presented at the recent ASH 2020 conference (American Society of [...]

Dec. 2020: Dr. Castillo Discusses Covid-19 Vaccines2021-01-27T17:34:01-05:00

Sept. 2020: Update on Management of WM and Future Research Directions

2021-01-18T17:16:20-05:00

An article entitled "2020 Update on Management and Future Directions" was published in the journal "Clinical Lymphoma, Myeloma and Leukemia".  You can see it here. 2020 Update on Management of WM

Sept. 2020: Update on Management of WM and Future Research Directions2021-01-18T17:16:20-05:00

October 2020: National Zoom Meeting with Dr. Treon

2021-01-27T17:32:54-05:00

In October, 2020, we had a national WMFC meeting (via Zoom, of course).  Our guest was Dr. Steve Treon of DFCI.  The topic of his presentation was "Genomic and Treatment Advances in WM".  The recording of the meeting is available, below. Genomic and Treatment Advances in WM

October 2020: National Zoom Meeting with Dr. Treon2021-01-27T17:32:54-05:00

Sept. 2020: BTK Inhibitors Transform Management of WM

2021-01-18T17:17:14-05:00

In an interview with OncLive in September, 2020, Dr. Treon from DFCI discussed the various BTK inhibitors that are now available or in trials. BTK Inhibitors transform WM management Along the same lines, a very valuable discussion was moderated by Dr. Treon, including experts from Europe and Australia.  This was recorded for the Oncology Learning Network in 2019. It is available as both a video and as a transcript. Video: BTK Inhibitors for the treatment of WM Transcript: BTK Inhibitors for the treatment of WM

Sept. 2020: BTK Inhibitors Transform Management of WM2021-01-18T17:17:14-05:00

How to Manage Cancer-Related Fatigue

2021-01-18T17:10:53-05:00

This animated video from Doc Mike Evans explains the effects of cancer-related fatigue. Dr. Evans explains that fatigue is the most common medical issue for cancer patients, ranking higher than pain or depression. He shares that cancer fatigue is very different than the fatigue most people face when they’re overtired or stressed, and that it has a profound effect on a person’s physical and mental health. Cancer-related fatigue can be brought on by a combination of things: the cancer itself, the side effects of cancer treatments like chemotherapy and radiotherapy, and depression or anxiety associated with having a chronic illness. [...]

How to Manage Cancer-Related Fatigue2021-01-18T17:10:53-05:00

October 2020: New Consensus Treatment Recommendations published (IWWM-10)

2021-01-27T17:31:03-05:00

The latest consensus on treatment recommendations has been published, from the tenth International Workshop for Waldenström Macroglobulinaemia (IWWM-10).  These consensus documents are, or should be, the basis for treatment everywhere.  National drug approvals, and provincial funding decisions, should (in theory) be in broad agreement with this. IWWM Consensus Guidelines -- 2020

October 2020: New Consensus Treatment Recommendations published (IWWM-10)2021-01-27T17:31:03-05:00

Sept-Nov 2020: Interviews with Dr. Ansell and Dr. Treon (Patient Power)

2021-01-18T17:18:51-05:00

The website "Patient Power" recently (Sept.-Nov., 2020) published a number of interviews, both as video and as transcripts. With Dr. Ansell from the Mayo Clinic: Will there be a cure for WM? With Dr. Treon from DFCI: Are we close to a cure for WM With Dr. Treon: How are BTK Inhibitors Changing WM outcomes With Dr. Treon: When should a patient seek treatment for WM

Sept-Nov 2020: Interviews with Dr. Ansell and Dr. Treon (Patient Power)2021-01-18T17:18:51-05:00

Sept. 2020: Health Canada Starts Review of BRUKINSA(R) (Zanubrutinib)

2021-01-18T17:23:10-05:00

Although this may appear as "another commercial press release from a drug company", this goes a little bit deeper for WM patients in Canada.  Beigene, having received priority status with Health Canada, is pursuing their approval for its 2nd-generation BTK-inhibitor, Zanubrutinib (Brukinsa®), for the treatment of WM.  Once Health Canada's review is complete, and assuming it is accepted, then Zanubrutinib would be on the same footing for WM patients in Canada as Ibrutinib.  Beigene will then apply to pCODR (see our very brief explanation of How Cancer Drugs Are Approved and Funded in Canada on our Canadian Questions Page), seeking [...]

Sept. 2020: Health Canada Starts Review of BRUKINSA(R) (Zanubrutinib)2021-01-18T17:23:10-05:00

August 2020: Treatment Guidance during Covid-19

2021-01-18T17:14:32-05:00

Consensus Statement Published August, 2020 In the light of the COVID-19 pandemic, the International Workshop on Waldenström Macroglobulinemia (IWWM) Treatment Recommendations Panel has published a consensus statement for the management of Waldenström Macroglobulinemia (WM) patients during this challenging time. The Panel followed the current recommendations by the American Society of Hematology, which have been modified accordingly to fit the specific realities associated with the management of WM. The Panel addressed questions related to treatment initiation, preferred therapies, minimizing visit to clinics and infusions centers, supportive care and guidance for WM patients in clinical trials. It also provided information on timing [...]

August 2020: Treatment Guidance during Covid-192021-01-18T17:14:32-05:00
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