Zanubrutinib was well tolerated and highly active in patients with Waldenström macroglobulinemia (WM), with more than 90% of patients experiencing a response, according to phase 1 data that were presented at the 10th International Workshop on Waldenström’s Macroglobulinemia… Continue reading
A head-to-head, open-label, multicenter, phase 3 clinical trial comparing the efficacy and safety of zanubrutinib (BGB-3111) with ibrutinib in patients with Waldenström macroglobulinemia (WM) is underway (ClinicalTrials.org Identifier: NCT03053440).1 The study also seeks to evaluate the… Continue reading
Zanubrutinib (BGB-3111), an investigational small molecule inhibitor of BTK, showed promising activity in patients with Waldenström macroglobulinemia (WM), according to updated results presented at the 2018 European Hematology Association Congress.
First author Judith Trotman, MBChB, FRACP, FRCPA, clinical professor of… Continue reading